Search results for " ultrasound complex spine and intrathecal"

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Ultrasound-guided lumbar puncture for nusinersen administration in spinal muscular atrophy patients.

2020

Background and purpose The purpose was to report the results of ultrasound-guided lumbar puncture for the administration of nusinersen in spinal muscular atrophy (SMA) patients with complex spines. Methods Eighteen SMA patients (five children, five adolescents and eight adults) with either severe scoliosis or spondylodesis were evaluated for ultrasound-guided lumbar puncture. Ultrasound was performed with a 3.5 MHz transducer to guide a 22 gauge × 15 mm needle, which was placed in the posterior lumbar space following a parasagittal interlaminar approach. Results Twelve patients had undergone spinal instrumentation (nine growing rods and three spinal fusion) whilst the other six showed sever…

Adultmusculoskeletal diseasesmedicine.medical_specialtyAdolescentlumbar puncture nusinersen spinal muscular atrophy ultrasound complex spine and intrathecalmedicine.medical_treatmentOligonucleotidesSpinal PunctureMuscular Atrophy Spinal03 medical and health sciences0302 clinical medicineLumbarmedicineHumans030212 general & internal medicineAdverse effectChildUltrasonography Interventionalmedicine.diagnostic_testbusiness.industryLumbar punctureUltrasoundSpinal muscular atrophySMA*medicine.diseaseSurgeryNeurologySpinal fusionNusinersenNeurology (clinical)business030217 neurology & neurosurgery
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